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Topics - Ageless the Drifter

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1
Spamalot / lotta broken imgur images on TZT lately
« on: November 25, 2014, 08:37:48 PM »
what is up with that


3
Agrulian Archives / Agrul where can I buy the cheapest textbooks.
« on: November 20, 2014, 03:24:09 PM »
Agrul where can I buy the cheapest textbooks.

I miss all the text books I abandoned when I moved away and cannot afford to replace them. Why don't libraries carry textbooks??

4
General Disconation / Anyone knowledgeable about mopeds? (Salviadiv?)
« on: November 17, 2014, 03:10:51 PM »
Was it Salviadiv who was the huge moped buff? Does he even lurk anymore?

Anyway I sold my car when I left Florida because public transit+bicycles were enough in Denver in the Summer and I thought I'd be overseas by now.

But while public transit+bicycle is sufficient in Portland in the Fall, it's not quite ideal, and it's definitely not gonna cut it for frequent long-hauls across town in the winter, so I'm looking to buy something small for getting around town.

I know mopeds are notoriously unreliable, though--I don't want all the savings on gas and insurance to go into constant repairs. So is there a reliable sort I should be looking out for? Preferably on the cheap (but I realize of course that those goals are largely mutually exclusive). Any other tips/advice?


5
General Disconation / Hoverboard (for real this time)
« on: November 17, 2014, 12:25:26 PM »
Just watched the video, didn't read anything, but it looks disappointing enough to be real. I'm guessing they used quantum locking to pull this off (edit: according to the second video this is in fact the case) and it only works on that metal halfpipe and that the halfpipe probably costs $100k per second to run and $14524352345245 to build

But still kinda neat

http://theridechannel.com/features/2014/11/tony-hawk-rides-hoverboard

Crave - Taking a spin on a real-life hoverboard

6
Spamalot / evil stick
« on: November 11, 2014, 11:04:57 PM »
Lol wtf

'Evil Stick' wand toy for toddlers reveals picture of a young girl slitting her wrists with knife

7
Spamalot / too many cooks
« on: November 07, 2014, 02:11:15 PM »
Infomercials - Too Many Cooks [adult swim]


Apparently aired on Adult Swim at 4AM without being listed anywhere. Watch the whole thing.

8
No airline'll take a dog in-cabin that can't walk around comfortably in an 8.5" tall carrier, and most won't check animals in cargo--which is probably super miserable for the dogs, anyway, and they don't allow sedation.

UPS and FedEx won't even ship mammals, period.

Wtf airplanes, how am I supposed to regale the ailing state of Florida with Euler's presence this xmas season??

9
Spamalot / A compelling video about Shia Labeouf
« on: October 23, 2014, 01:24:39 PM »
"Shia LaBeouf" Live - Rob Cantor

10
http://www.sun-sentinel.com/news/local/southflorida/os-state-of-south-florida-20141021-post.html



Officials in the City of South Miami have passed a resolution in favor of splitting the state in half so South Florida would become the 51st state.

Vice Mayor Walter Harris proposed the resolution and it passed with a 3-2 vote at the city commission meeting on Oct. 7.

Harris told the commission that Tallahassee isn't providing South Florida with proper representation or addressing its concerns when it comes to sea-level rising.
Officials want South Florida to break off into its own state
Officials in the City of South Miami have passed a resolution in favor of splitting the state in half so South Florida would become the 51st state.

"We have to be able to deal directly with this environmental concern and we can’t really get it done in Tallahassee," Harris said. "I don’t care what people think -- it’s not a matter of electing the right people."

Mayor Philip Stoddard agreed with Harris' reasoning, saying he's advocated for secession for the past 15 years but never penned a resolution.

“It’s very apparent that the attitude of the northern part of the state is that they would just love to saw the state in half and just let us float off into the Caribbean," Stoddard said. "They’ve made that abundantly clear every possible opportunity and I would love to give them the opportunity to do that.”

But the vote wasn't unanimous. Commissioners Gabriel Edmond and Josh Liebman voted against the resolution with Edmond, a history teacher, being the most vocal about it.

"I just want you guys to be careful because if you vote for this you’re setting a precedent that if other people in this city don’t like our representation or feel we’re not responsive to them they might say ‘we want to break away from the city of South Miami’.”
State of South Florida
Officials in the city of South Miami proposed that each county shown in orange separate from the rest of the state to become the state of South Florida. (Charles Minshew)

The resolution lists the northern border of what would be the state of South Florida as being Brevard, Orange, Polk, Hillsborough and Pinellas counties.

Orange County is particularly important because that's where the South Florida Water Management District begins, Harris said. It was even suggested that a Central Florida city could possibly be the state of South Florida's capitol.

In total, the proposed 51st state would include 24 counties.


The resolution's 3-2 approval paved the way for it to be sent to the governing bodies of the proposed South Florida counties for consideration. In order for secession to be enacted, however, the measure would require electorate approval from the entire state and Congressional approval.



11
Tech Heads / Ugh
« on: October 18, 2014, 08:47:40 PM »
Finally decided to say fuck it and put Windows back on my box after being throttled in productivity by linux for ~4 months

Shortly beforehand I'd started getting S.M.A.R.T test notices saying my HD is gonna die soon

But I went ahead and put Windows back on anyway. Spent a day getting it all set up because I had some trouble with drivers since I didn't use the original Win disk ASUS gave me that included drivers and whatnot.

The within like five minutes of finally getting my touchpad all set up the way I like it (more or less, the new Elantech drivers are shit), my charger completely gave up the ghost.

So I borrowed a charger from a friend who doesn't have a laptop anymore and said I could keep it. Turned out to be the right one, by chance. Plug it in, nothing happens. Got a bad DC jack. But it's not worth replacing the jack because the HD could tank any time. Replacing both'd be cheaper than buying a new laptop, I guess, but I'm gonna be without for a while, anyway--moving halfway across the country twice in 6 months has left me broke as fuuuuuuu

Just ugh.

12
http://www.theverge.com/2014/10/10/6954135/barcelona-comedy-club-is-charging-customers-by-the-laugh

Pay per Laugh | TeatreNeu on Vimeo


Even though this could only lower the cost of attendance I feel like the distraction of wondering how much money I'm spending and trying to control it would spoil the experience a bit.


13
General Disconation / World's Scariest Haunted House
« on: October 10, 2014, 10:47:46 PM »
http://canyouactually.com/one-of-the-most-extreme-and-disturbing-haunted-houses-on-the-planet/



This isn’t your average haunted house… it’s honestly a walk through your worst nightmares, and by walk I mean gauntlet. Located in San Diego, McKamey Manor is one of the most intense and scariest haunted houses on the planet….. and that’s putting it lightly. Russ McKamey is the evil genius behind this haunt that he started about 14 years ago.



Here are a few requirements you must pass to even be able to enter: you now must be 21 years of age (previously was 18), you’re required to sign a wavier, and you must be in excellent physical condition. Only two people go in at a time, and get this… it can last anywhere from 4 – 7 hours. They actually now only take four people through the haunted house each week.



They’re allowed to touch you, gag you, put a bag over your head and pretty much anything that’s not illegal. It’s also one of the few haunted houses that stays open year round, and the only haunted house in the world where admission is free….. I’m serious. Check out the promo video below, it’s from 2013.

Think you can handle it?? Check out their website here and make your reservation…. oh and just because you make a reservation doesn’t mean you will get selected. It’s almost like by invitation only, or how Russ likes to call it, a “Golden Ticket”.

۾



I'm guessing people subject themselves to this to prove they're tough/build character and in most cases come out with PTSD. The fact that it can last anywhere between 4 and 7 hours makes me wonder if they don't just keep you in certain locations till they break you.


14
General Disconation / Art people + technophiles: Tablet shopping
« on: October 10, 2014, 02:34:37 PM »
Hey ya'll

I'm broke as fuck but I want to start putting away money for a touch-screen tablet for drawing on, and I dunno what's good these days. If I remember correctly, back in the day "tablet" pretty much meant "pen-mouse pad with a screen in it" and was primarily a digital art thing, but now "tablet" means "Galaxy S_ with a larger screen" and I dunno if that kind of thing is worth a shit for what I need it for.

So what's good for that these days? I imagine the top of the line is way outside my budget if I wanna be able to buy the thing in the next year, but I don't need bleeding edge, just not hardly-functional. I think Gabe from Penny Arcade draws on a Surface Pro, so maybe that's pretty good?

I figured we've got at least a couple serious artists here that might have opinions.

15
General Disconation / Twin Peaks revival
« on: October 06, 2014, 03:09:35 PM »
In case your facebook news feed isn't as flooded with excitement about this as mine is

http://variety.com/2014/tv/news/twin-peaks-revival-to-air-on-showtime-in-2016-1201322329/



“Twin Peaks,” the ABC series that was a forerunner of today’s offbeat serialized cable dramas, is coming back to life with nine new episodes to air on Showtime in 2016.

Series creators David Lynch and Mark Frost are working away on the scripts, with Lynch planning to direct all nine episodes. The episodes are expected to bow in early 2016, which would coincide with the 25th anniversary of the show’s demise after two seasons on ABC in 1990 and 1991.

The new segs will be set in the present day and continue storylines established in the second season. Frost emphasized that the new episodes will not be a remake or reboot but will reflect the passage of time since viewers last checked in with key characters. As part of the deal, Showtime will rerun episodes from the original series’ first two seasons leading up to the 2016 premiere.

Frost would not elaborate on plot details or even the characters that will come into play. But the story threads that will picked up were “baked in to the last episode,” Frost told Variety. He called it “the next chapter of the story” and said that the passage of 25 years will be an important element in the plot.

“For those followers of the show who felt bereft when the show ended where it did all those years ago are going to like where it goes from here,” Frost assured. “And we hope that a lot of people who haven’t been to Twin Peaks yet are going to be equally interested in where the story goes from where we left off.”

“Twin Peaks” was ahead of its time in its unusual, often surreal approach to telling the yarn of a murder mystery in a fictional small town in Washington state. The show bowed with a ton of buzz — Lynch was red-hot as a feature helmer at the time — but it had little in the way of a sustained audience by broadcast TV standards of the day.

The series has remained a cult favorite over the years and thus was a ripe candidate for revival amid the general mania in the TV biz for reinventing vintage film and TV titles.

Lynch and Frost have retained ownership of “Twin Peaks” all these years. CBS has distribution rights to the show through the deficit-financing pact that Lynch/Frost Prods. set back in the day with Aaron Spelling’s Worldvision distribution arm, which CBS now controls.

Another key connection that helped the new-model “Twin Peaks” land at Showtime is the pay cabler’s Gary Levine, exec VP of original programming, who was the ABC exec who developed and championed the show during its original run.

Lynch and Frost have talked about taking another run at the Twin Peaks world over the years, but the effort got serious about three years ago when the two had one of their semi-regular lunches at Hollywood’s Musso and Frank Grill. It was not lost on either of them that “Twin Peaks” had proved to be a TV pioneer in many respects. Aspects of the show that were seen as a handicap in the ABC days are now pillars of the contempo generation of edgy cable and pay cable series.

“I always felt that in ‘Twin Peaks’ we were more or less filming a novel — drilling down to a level of detail you weren’t used to seeing in network storytelling,” Frost said. “Over the years a lot of people have credited us with inspiring them to think differently in how to tell stories. Now that we’re doing (the show) again, I’m happy to come back and get in on the action.”

Lynch and Frost didn’t shop the series around. Showtime was a natural home because of the latitude offered by pay cable, plus the comfort level offered by the connection with Levine.

“Showtime was the place we felt most comfortable going to after meeting with Gary and (Showtime prexy) David Nevins and seeing their passion for the show,” Frost said. “Gary we consider a good friend and David I’ve known for quite a while.”

There’s no word yet about casting. In the original series, Kyle MacLachlan (pictured) played the pivotal role of the Agent Dale Cooper, the FBI agent who comes to the small town to investigate the murder of homecoming queen Laura Palmer.

After that mystery was solved, the show explored even more seamy goings-on and oddball characters in the town. The pilot for the original series was shot on location in Washington state, but subsequent episodes were primarly lensed on stages in the San Fernando Valley. There’s no decision yet on a shooting location for the new segs.

Frost said it was still to be determined whether the revival will be a one-time limited series or an ongoing effort.

“The proof will be in the pudding. If we have a great time doing it and everybody loves it and they decide there’s room for more, I could see it going that way,” he said. The original “Twin Peaks” premiered on April 8, 1990 and had its last original telecast in June 1991. A prequel story, “Twin Peaks: A Fire Walk with Me,” was released as a feature by New Line in 1992.

The TV series has endured for a new generation of fans through periodic homevid releases and more recently, a streaming pact with Netflix. The AFI hosted a tribute to the show in Los Angeles in July in connection with the Blu-ray/DVD release “Twin Peaks: The Entire Mystery.”

Given the show’s legacy and the rabid fandom it has inspired, Frost admitted that he and Lynch feel the pressure to make the new episodes worthy additions to the canon.

“We can’t rest on our laurels,” he said, which is a key reason why Lynch has committed to directing all nine hours.

“This show is a kind of thanks to all of the incredibly passionate fans we’ve had over the years that have kept the show alive and passed it down to the next generation,” Frost said. “We’ve been lucky enough to have one of the coolest, most intelligent, most inquisitive group of people attracted to our show. We’re happy for them that the show is coming back.”

In a statement issued by Showtime, Lynch and Frost quipped: “The mysterious and special world of Twin Peaks is pulling us back. We’re very excited. May the forest be with you.”


16
Was kinda disappointed in the article after reading the headline--I don't think the smarm is quite warranted beyond the fact that it's kinda nice to see people who think there shouldn't be child labor laws get suckered. It's not like this instance really gives any evidence against the legitimacy of their ideology, though, since the community never had a chance to get going due to external government interference.

Still thought it was comment-worthy, though.



http://www.addictinginfo.org/2014/09/15/libertarian-utopia-styled-after-ayn-rand-book-spectacularly-falls-apart-almost-immediately/

A community made up of American ex-pats deep in the South American hills of Chile – far away from America’s annoying taxes, healthcare mandate, and legal abortions — was supposed to be a libertarian paradise of rugged individualism. Instead it cost many of the people who bought into it almost everything, and now is buried under lawsuits — a reminder that everything that glitters is not inflation-proof, Ron Paul-backed gold.

It seems pretty obvious that basing one’s society on a single work of (poorly written) fiction is folly, but for many adherents of Ayn Rand and her seminal book of Objectivist allegorical grandstanding, Atlas Shrugged isn’t just any book. It’s about as close to the Bible that many libertarians have — apart from the Bible, of course. It’s influenced an astounding number of conservative public figures — from Ron Paul to Rand Paul to Ronald Reagan. Paul Ryan, Mitt Romney’s Rand-loving running mate and probable 2016 presidential contender, said it was his favorite book growing up.

    “I grew up reading Ayn Rand, and it taught me quite a bit about who I am and what my value systems are,” the congressman told a convention of Rand followers in 2005. Rand was “the reason I got involved in public service.” (source)

In many ways, the entire Republican ethos — hard-working job creators having their vitality leeched by lazy “takers” — stems from Rand and her rigidly anti-socialism ideology. In Atlas Shrugged, Rand explores the fantasy of leaving those poor, lazy, uneducated leeches behind, creating a new society of self-sufficient ubermenschs, living free from governmental or social tyranny. That is where the mysterious John Galt comes in. A man set on freeing these enslaved freedom-lovers from the shackles of the moochers. He creates a mountain home for his followers: Galt’s Gulch.

Let’s call it what it is: Libertarian fan fiction. An artificial world where hard work is all you need, and poor people are responsible for their own misery. In fact, Rand goes a bit further than what many — even fervent “Rand-heads” — find comfortable. Such was Ayn Rand’s fury over socialism that even hallowed institutions that Americans find important were excised under the Objectivism razor. Ryan might not admit it, but that book he loves advocates for getting rid of everything from public education, to farming subsidies, to any form of welfare. If that seems a bit drastic, well hey, Rand never claimed to be sentimental.

Unfortunately, the real world is a bit more complicated — socioeconomics, cycles of poverty, economic disparity, lack of education, racism and sexism; a myriad of factors contribute to an individual’s lot in life. But for some, the dream didn’t die with the close of the book. For some, Galt’s Gulch could be real if only someone would create it.

In the book, Galt’s Gulch is based in the Western United States. Unfortunately for today’s Libertarians, “out west” isn’t far enough from America’s socialized oppression. Convinced that America is on the verge of economic collapse, they fled the country and headed south.

Billed as Galt’s Gulch Chile, the South American would-be community is 11,000 acres of pure, unregulated freedom.

According to, Jeff Berwick, one of the project’s early promoters:

    With the oppression of the over regulated, over taxed, war riddled and welfare riddled society consuming the world, Ayn Rand’s famous protagonist character, John Galt, came to conclude that he would not use his talents to support such a society any longer…driving him to create a community where scientists, inventors, entrepreneurs and many others would come together to escape from the confines of their daily lives to not only be free…but to thrive.

    In today’s world, it is becoming more and more difficult to find true freedom from very much the same oppressive forces Ayn Rand wrote of…which drove John Galt and others to a place where they found their freedom, success and peace of mind.

    Welcome to Galt’s Gulch Chile!

The community is the brainchild of Ken Johnson and a collection of investors. In 2013, when the project was just shaping up, Mother Jones went down to Chile to see how things were coming along.

    Welcome to Galt’s Gulch Chile, a libertarian refuge from the coming economic, social, and political collapse of the United States. The would-be free-market utopia, named after the mountain redoubt of the protagonist of Ayn Rand’s Atlas Shrugged, is taking advance payments (Bitcoins gladly accepted) for parcels on its 11,000 acres.

    Joining Johnson, the project’s managing partner, are three prospective buyers: a retiree from Oregon, a California-based expert in moving assets offshore, and another retiree who doesn’t want to give much in the way of personal data. “Oh, the NSA’s here too?” he says the first time he sees my audio recorder. The men talk of a coming financial meltdown caused by the Federal Reserve, followed by a Homeland Security police state. They’re ready to get out with their silver, guns, and organic honey—but not quite ready to sacrifice fast internet, access to an international airport, and a time zone convenient for Skyping with the doomed sheeple back home. Throw in low taxes, privatized social security, and a Mediterranean climate, and you have Chile.

For the price of $48,500 you too could own a piece of Galt’s Gulch (specifically, one-and-a-half acres of it). Amazingly, people cashed in their retirements and did just that.

A year later and things have completely unraveled. According to one person who spent a great deal of her savings on this grand experiment, the thing was doomed from the start. Based on her description, what you are left with is the growing sense that this isn’t just a case of arrogant stupidity, this is a downright scam.

Writing out of The Dollar Vigilante, a website devoted to the libertarian movement, the investor, Wendy McElroy, who describes herself as an individualist anarchist, documents the nightmare of Galt’s Gulch Chile:

    Many have wondered about the status of Galt’s Gulch Chile (GGC), the libertarian community that was planned and sold in lots as a liberty oasis for those who wished to live freedom before they died. My husband and I purchased an option on 1.25 acres in July 2013. Others bought 10- or 25-acre lots and some invested in the agricultural side of the venture; extremely savvy investors committed small fortunes. GGC has been an unexpectedly wild ride since then.

After throwing in considerable money, McElroy received an email from a concerned friend, essentially calling the entire operation into question. At first McElroy dismisses the email, at the harried assurance of Ken Johnson. Later, it begins to be apparent that the concerned friend was disturbingly on the money (emphasis added).

    There will be no zoning for the 1.25-acre lots or other arrangements of less than 10 acres.  GGC is an environmentally protected area and it would take the political movement of heaven and earth to allow a community based on small lots to be officially approved. I had the opportunity to ask a question of the salesman who showed my husband and me “our property.” I claimed it because I fell head over heels for the most beautiful tree I’ve ever seen. I felt an instant connection as though the two of us were old souls who had found each other. I could believe it, I could see it… waking up each morning and having coffee under that tree, telling it about my plans for the day. Months later, in a Skype conference, I asked the then-GGC-alienated salesman, “When you ‘sold’ us the property, when you printed out a photo from your phone that read ‘Wendy’s tree,’ did you know you could not legally sell us the lot you were offering?” He said, “That is correct.”

Since writing that, the Galt’s Gulch Chile founders have been engaged in a series of increasingly dramatic legal and personal squabbles. Litigation is being thrown around, as are ad hominem attacks. Nearly all of the anger is directed at Ken Johnson.  One former co-owner, Jeff Berwick, who happens to run The Dollar Vigilante website, has called Johnson a sociopath and a fraud. A Facebook community has been established calling itself “Galt’s Gulch Chile Rehab and The Exposing of Ken Johnson” to serve as a support group for other investors who felt they were ripped off.

Meanwhile, Galt’s Gulch owes “hundreds and hundreds of thousands of dollars to hardware stores [and] service providers” in Chile for work done in preparation for the community. As the pyramid scheme of investors collapses, it seems likely that those workers – many of them poor laborers from small Chilean towns — will go unpaid. The workers being ripped off by the moochers? How very Randian.

The Grim Reaper lingers nearby. By the end of August, the entire online existence of Galt’s Gulch Chile had been scrubbed from the web. Every promotional YouTube video made to entice suckers freedom-lovers has been taken down. The GGC website comes back with an error message. Ken Johnson is in the wind.

It’s almost as if basing a community around people who hate other people and don’t want to have to pay for any services that don’t directly and concretely benefit themselves is inherently unstable. Who would have thought?


17
Not really that surprising in hindsight, but interesting, anyway.


http://www.usatoday.com/story/news/nation/2014/09/15/genetic-cause-schizophrenia/15535557/


New research shows that schizophrenia is not a single disease, but a group of eight distinct disorders, each caused by changes in clusters of genes that lead to different sets of symptoms.

The finding sets the stage for scientists to develop better ways to diagnose and treat schizophrenia, a mental illness that can be devastating when not adequately managed, says C. Robert Cloninger, co-author of the study published Monday in the American Journal of Psychiatry.

"We are really opening a new era of psychiatric diagnosis," says Cloninger, professor of psychiatry and genetics at the Washington University School of Medicine in St. Louis. Cloninger says he hopes his work will "allow for the development of a personalized diagnosis, opening the door to treating the cause, rather than just the symptoms, of schizophrenia."

Clonginger and colleagues found that certain genetic profiles matched particular symptoms. While people with one genetic cluster have odd and disorganized speech – what is sometimes called "word salad" – people with another genetic profile hear voices, according to the study, funded by the National Institutes of Health.
XXX_schizophrenia02

Dr. C. Robert Cloninger, Washington University School of Medicine, and colleagues found that certain genetic profiles matched particular symptoms of schizophrenia.(Photo: Robert Boston, Washington University)

Some genetic clusters gave people higher risks of the disease than others, according to the study, which compared the DNA of 4,200 people with schizophrenia to that of 3,800 healthy people.

One set of genetic changes, for example, confers a 95% chance of developing schizophrenia. In the new study, researchers describe a woman with this genetic profile who developed signs of the disorder by age 5, when she taped over the mouths of her dolls to make them stop whispering to her and calling her name. Another patient – whose genetic profile gave her a 71% risk of schizophrenia – experienced a more typical disease course and began hearing voices at age 17.

The average person has less than a 1% risk of developing schizophrenia, Cloninger says.

Psychiatrists such as Stephen Marder describe the the study as a step forward. Today, doctors diagnose patients with mental illness with a process akin to a survey, asking about the person's family history and symptoms, says Marder, a professor at the David Geffen School of Medicine at the University of California-Los Angeles.

"It underlines that the way we diagnose schizophrenia is relatively primitive," Marder says.

Patients may wait years for an accurate diagnosis, and even longer to find treatments that help them without causing intolerable side effects.

Doctors have long known that schizophrenia can run in families, says Robert Freedman, editor in chief of the American Journal of Psychiatry and chair of psychiatry at the University of Colorado Anschutz Medical Campus. If one identical twin has schizophrenia, for example, there is an 80% chance that the other twin has the disease, as well.

In the past, doctors looked for single genes that might cause schizophrenia, without real success, Freedman says.

The new paper suggests that genes work together like a winning or losing combination of cards in poker, Freedman says. "This shows us that there are some very bad hands out there," Freedman says.
XXX_schizophrenia01

Doctors have known for years that breast cancer is not one disease, but at least half a dozen diseases driven by different genes, says study co-author Igor Zwir, research associate in psychiatry at Washington University.(Photo: Robert Boston, Washington University)

In some cases – in which a genetic profile conveys close to a 100% risk of schizophrenia – people may not be able to escape the disease, Cloninger says. But if doctors could predict who is at high risk, they might also be able to tailor an early intervention to help a patient better manage their condition, such as by managing stress.

Doctors don't yet know why one person with a 70% risk of schizophrenia develops the disease and others don't, Clonginger says. It's possible that environment plays a key role, so that child with a supportive family and good nutrition might escape the diagnosis, while someone who experiences great trauma or deprivation might become very ill.

The study also reflects how much has changed in the way that scientists think about the genetic causes of common diseases, Marder says. He notes that diseases caused by a single gene – such as sickle-cell anemia and cystic fibrosis – affect very few people. Most common diseases, such as cancer, are caused by combinations of genes. Even something as apparently simple as height is caused by combinations of genes, he says.

Doctors have known for years that breast cancer is not one disease, for example, but at least half a dozen diseases driven by different genes, says study co-author Igor Zwir, research associate in psychiatry at Washington University. Doctors today have tests to predict a woman's risk of some types of breast cancer, and other tests that help them select the most effective drugs.

Those sorts of tests could be extremely helpful for people with schizophrenia, who often try two or three drugs before finding one that's effective, Cloninger says.

"Most treatment today is trial and error," Cloninger says.

If doctors could pinpoint which drugs could be the most effective, they might be able to use lower doses, producing fewer of the bothersome side effects that lead many patients to stop taking their medication, Cloninger says.


18
Homeless Millennial Survives By Picking Up Women Every Night [Insights] | Elite Daily


jfc

19
https://www.kickstarter.com/projects/1316851183/the-new-8-bit-heroes-new-nes-game-and-creation-doc

Dude I know is making a new NES game--like in-cartridge, playable-in-console NES game. I don't think this is the first time it's ever been done since Nintendo stopped selling NESs but I still think it's a pretty cool project. The cartridge will also contain a second game that's playable on the PC and interacts with the NES game in various ways, which I thought was a neat idea.

The guy running it is a pretty cool fellow and is super passionate about the projects he does. Mostly he makes documentaries, and he's going to be making one about the making of the game. He already got backed by the guy who made King of Kong.

The team is pretty solid. The pixel art guy does some killer work.



I'm not on the team but I got my foot in the door a little late. I'll be doing little things here and there along the way (first task is to draw up a world-map for the instruction manual, for instance) and hoping to get a more substantial spot if the kickstarter really takes off.

Anyway ya'll should check it out.

20
lies terribly to cover their ass

gawker.com/urban-outfitters-sells-vintage-blood-spattered-kent-s-1634786441





In a strident display of bad taste, Urban Outfitters was selling a $130 "vintage" Kent State sweatshirt with fake blood splatter this weekend as an apparent homage to the 1970 shooting that left four dead. The sweatshirt is now listed as "sold out" in Urban Outfitter's online store. The shirt appears to have been a one-off sale, the site imploring customers, "We only have one, so get it or regret it!"

As People discovered, the shirt appears to have gone up for sale on eBay for $550—the auction ended earlier this morning with zero bids.

Urban Outfitters Sells "Vintage" Blood-Spattered Kent State Sweatshirt

Update, 10:21 a.m.: Urban Outfitters has issued the following statement, via their Twitter account:

    Urban Outfitters sincerely apologizes for any offense our Vintage Kent State Sweatshirt may have caused. It was never our intention to allude to the tragic events that took place at Kent State in 1970 and we are extremely saddened that this item was perceived as such. The one-of-a-kind item was purchased as part of our sun-faded vintage collection. There is no blood on this shirt nor has this item been altered in any way. The red stains are discoloration from the original shade of the shirt and the holes are from natural wear and fray. Again, we deeply regret that this item was perceived negatively and we have removed it immediately from our website to avoid further upset.

Update, 11:00 a.m.: Kent State has issued their own statement in response to the shirt:

    May 4, 1970, was a watershed moment for the country and especially the Kent State family. We lost four students that day while nine others were wounded and countless others were changed forever.

    We take great offense to a company using our pain for their publicity and profit. This item is beyond poor taste and trivializes a loss of life that still hurts the Kent State community today.

    We invite the leaders of this company as well as anyone who invested in this item to tour our May 4 Visitors Center, which opened two years ago, to gain perspective on what happened 44 years ago and apply its meaning to the future.




Not the most outrageously tasteless thing I've ever heard of being sold by a major retailer, it's just surprising to see this being sold by UO to hipsters rather than by Hot Topic to angsty mall goths or something. And also hilarious that they're claiming it was unintentional and the sweater is "unaltered"

21
Spamalot / Unofficial garage box thread
« on: September 12, 2014, 12:32:33 PM »

22
General Disconation / Shadow of the Collosus movie
« on: September 04, 2014, 05:21:22 PM »


http://variety.com/2014/film/news/andres-muschietti-to-direct-shadow-of-the-colossus-for-sony-1201297802/

Sony Pictures has tapped Andrés Muschietti to direct the highly-anticipated adaptation of the video game “Shadow of the Colossus.”

Barbara Muschietti will come on board the project to produce alongside Kevin Misher, who produces through his Misher Films banner.

Set in an epic-scale world filled with mythic giants and disembodied spirits, the story will follow a young man attempting to save his lost love by accomplishing a seemingly impossible task… the destruction of the colossi who roam the forbidden land.

Seth Lochhead is penning the script. Michael De Luca and Andrea Giannetti will oversee the project for the studio.

“We knew we had our director once we heard Andy’s take on the material – it was genius,” De Luca said. “The themes, characters and supernatural elements of the story have incredible international appeal with fans of the game in the millions.”

“Shadow of the Colossus,” published by Sony Computer Entertainment Worldwide Studio for PlayStation 2, was directed and designed by Japanese video game developer Fumito Ueda. It was named Best Game at the 6th Annual Game Developer’s Choice Awards. The game has sold over 2.7 million copies worldwide to date.

Muschietti, who is repped by WME, most recently directed the Universal pic “Mama” starring Jessica Chastain.



Director's the guy who directed Mama, which I remember hearing was incredibly scary but have not seen and do not know anything about. I'm gonna go ahead and bet this movie winds up being a let-down, though--them's some hard shoes to fill.

23


http://www.nytimes.com/2014/09/03/upshot/the-economic-price-of-colleges-failures.html?smid=fb-nytimes&smtyp=cur&bicmp=AD&bicmlukp=WT.mc_id&bicmst=1409232722000&bicmet=1419773522000&abt=0002&abg=1



Four years ago, the sociologists Richard Arum and Josipa Roksa dropped a bomb on American higher education. Their groundbreaking book, “Academically Adrift,” found that many students experience “limited or no learning” in college. Today, they released a follow-up study, tracking the same students for two years after graduation, into the workplace, adult relationships and civic life. The results suggest that recent college graduates who are struggling to start careers are being hamstrung by their lack of learning.

“Academically Adrift” studied a sample of students who enrolled at four-year colleges and universities in 2005. As freshmen, they took a test of critical thinking, analytic reasoning and communications skills called the Collegiate Learning Assessment (C.L.A.). Colleges promise to teach these broad intellectual skills to all students, regardless of major. The students took the C.L.A. again at the end of their senior year. On average, they improved less than half of one standard deviation. For many, the results were much worse. One-third improved by less than a single point on a 100-point scale during four years of college.

This wasn’t because some colleges simply enrolled smarter students. The nature of the collegiate academic experience mattered, too. Students who spent more time studying alone learned more, even after controlling for their sociodemographic background, high school grades and entrance exam scores. So did students whose teachers enforced high academic expectations. People who studied the traditional liberal arts and sciences learned more than business, education and communications majors.

Yet despite working little and learning less — a third of students reported studying less than five hours a week and half were assigned no long papers to write — most continued to receive good grades. Students did what colleges asked of them, and for many, that wasn’t very much.

“Academically Adrift” called into question what college students were actually getting for their increasingly expensive educations. But some critics questioned whether collegiate learning could really be measured by a single test. Critical thinking skills are, moreover, only a means to an end. The end itself is making a successful transition to adulthood: getting a good job, finding a partner, engaging with society. The follow-up study, “Aspiring Adults Adrift,” found that, in fact, the skills measured by the C.L.A. make a significant difference when it comes to finding and keeping that crucial first job.

The students in the study graduated in the teeth of the post-Great Recession labor market, in mid-2009. Two years later, 7 percent were unemployed, consistent with national studies finding that recession-era college graduates were more likely to be unemployed than recent college grads in better economic times, but much less likely to be jobless than young adults with no college degree. An additional 16 percent were underemployed, working less than 20 hours a week or in an unskilled job such as grocery store cashier.

Even after statistically controlling for students’ sociodemographic characteristics, college majors and college selectivity, those who finished school with high C.L.A. scores were significantly less likely to be unemployed than those who had low C.L.A. scores. The difference was even larger when it came to success in the workplace. Low-C.L.A. graduates were twice as likely as high-C.L.A. graduates to lose their jobs between 2010 and 2011, suggesting that employers can tell who got a good college education and who didn’t. Low-C.L.A. graduates were also 50 percent more likely to end up in an unskilled occupation, and were less likely to be satisfied with their jobs.

Remarkably, the students had almost no awareness of this dynamic. When asked during their senior year in 2009, three-quarters reported gaining high levels of critical thinking skills in college, despite strong C.L.A. evidence to the contrary. When asked again two years later, nearly half reported even higher levels of learning in college. This was true across the spectrum of students, including those who had struggled to find and keep good jobs.

Through diplomas, increasingly inflated grades and the drumbeat of college self-promotion, these students had been told they had received a great education. The fact that the typical student spent three times as much time socializing and recreating in college as studying and going to class didn’t change that belief. Nor did unsteady employment outcomes and, for the large majority of those surveyed, continued financial dependence on their parents.

Students who were interviewed in depth by Dr. Arum and Dr. Roksa put great stock in collegiate social experiences that often came at the expense of academic work, emphasizing the value of the personal relationships they built. But only 20 percent found their most recent job through personal contacts, and of those, less than half came from college friends. And while the recent graduates were gloomy about the state of the nation, they professed strong belief in their own future success. The vast majority thought their lives would be better than that of their parents. “They learned from the experts that they can do well with little effort,” Mr. Arum told me, “so they’re optimistic.”

On average, college graduates continue to fare much better in the job market than people without degrees. But Mr. Arum and Ms. Roksa’s latest research suggests that within the large population of college graduates, those who were poorly taught are paying an economic price. Because they didn’t acquire vital critical thinking skills, they’re less likely to get a job and more likely to lose the jobs they get than students who received a good education.

Yet those same students continue to believe they got a great education, even after two years of struggle. This suggests a fundamental failure in the higher education market — while employers can tell the difference between those who learned in college and those who were left academically adrift, the students themselves cannot.




24
http://www.lovebscott.com/news/say-what-now-ceelo-green-tries-to-define-rape-on-twitter-says-its-not-r-pe-if-you-dont-remember-it



CeeLo Green recently pled “no contest” to charges stemming from a 2012 incident in which he allegedly slipped a 33-year-old woman ecstasy during a dinner in Los Angeles. The woman claims she woke up next to CeeLo naked with no recollection of their night, but CeeLo’s lawyer says they had ‘consensual relations’.

No sex charges were filed due to a lack of evidence, and his no contest plea allowed him to maintain his innocence. He did get sentenced to three years of probation and 45 days of community service for furnishing ecstasy.

For CeeLo, that wasn’t enough. He decided he needed to speak out publicly and attempt to clear his name. The only problem is that he ended up sounding much more like a rapist. He gave his thoughts on what qualifies as rape and what doesn’t.

“If someone is passed out they’re not even WITH you consciously,” he tweeted. “People who have really been raped REMEMBER!!!”

It got worse. He continued to dig himself in to a deeper hole until he eventually deleted the entire rant. Check out a few of his other tweets below.




25
General Disconation / sepak takraw
« on: August 18, 2014, 12:32:20 PM »
http://en.wikipedia.org/wiki/Sepak_takraw

Sepak Takraw Sport In Thailand


It's like someone took soccer and made it not shitty and boring + left all the cool parts

26
General Disconation / No thread on the Ferguson riots huh
« on: August 15, 2014, 10:58:13 AM »

27
Spamalot / dog trying to save fish out of water
« on: August 13, 2014, 07:19:40 PM »
Dog Tries To Save Fish Out Of Water


 :sad: :sad:

28
Palin's Response to Elizabeth Warren’s Progressive Commandments


Been Far?



29
General Disconation / RL Improbability Drive
« on: July 31, 2014, 07:30:02 PM »
http://www.pbs.org/wgbh/nova/next/space/improbable-thruster-seems-work-violating-known-laws-physics/?utm_source=facebook&utm_medium=pbsofficial&utm_campaign=nova_next

Every action creates an equal and opposite reaction. It’s perhaps the best known law of physics, and Guido Fetta thinks he’s found a way around it.

According to classical physics, in order for something—like a spaceship—to move, conservation of momentum requires that it has to exert a force on something else. A person in roller skates, for example, pushes off against a wall; a rocket accelerates upward by propelling high-velocity combusted fuel downward. In practice, this means that space vessels like satellites and space stations have to carry up to half their weight in propellant just to stay in orbit. That bulks up their cost and reduces their useful lifetime.

With that in mind, Fetta designed what he called the “Cannae Drive,” which he claims creates momentum without pushing against seemingly anything at all. He recently convinced a team at NASA to test it, who presented the results at a conference yesterday.
cannae-drive-schematic
A schematic of the lower half of the Cannae Drive cavity

The NASA team, using a torsion pendulum, or a device that can measure minute forces, found that Fetta’s drive created 30-50 micronewtons’ worth of thrust. That’s not a lot of force—even one whole Newton is less than the weight you feel in your hand when you hold an iPhone—but according to the laws of classical physics, Fetta’s device shouldn’t have produced any at all.

Fetta, an independent inventor with a background in chemical engineering, explains that the drive is a “superconducting resonating cavity.” According to him, the cavity is designed with little wells along the bottom edge to trap electrons, so that when electromagnetic waves bounce around inside the cavity, more electrons push up on the top surface of the cavity than push down on the bottom. This imbalance, Fetta says, creates upward thrust.

In the paper, NASA seemed reluctant to dive into the drive’s mysterious physics. They wrote nothing to suggest how, exactly, the force was produced. In fact, the mysterious drive actually worked even when they modified it in such a way it shouldn’t have produced any thrust, suggesting the mechanics of the system are hazily understood. The one exception was a reference, in the paper’s abstract, to a possible interaction with the “quantum vacuum virtual plasma.”

David Hambling, writing for Wired.co.uk, explains what that might mean:

    This […] implies that the drive may work by pushing against the ghostly cloud of particles and anti-particles that are constantly popping into being and disappearing again in empty space.

A similar “microwave thruster” drive, proposed by British engineer Roger Shawyer, was tested last year by a Chinese team. Those results were largely dismissed. NASA’s results, though, seem to lend some credence to the idea that supposedly impossible “unbalanced forces” can actually result in momentum.

The NASA team stresses that the drive needs to be tested more thoroughly—but if it really works, it could be a major breakthrough for deep-space exploration. Because a drive like this could be powered solely by solar energy, satellites and space stations could stay on course and in orbit without having to lug around so much propellant.

Hambling:

    A working microwave thruster would radically cut the cost of satellites and space stations and extend their working life, drive deep-space missions, and take astronauts to Mars in weeks rather than months.

We still don’t know if Fetta’s propellant-less drive works the way he claims it does—and we need more evidence before we can be sure that it even works at all. But if it does—watch out, space. We’re coming for you.


Ok it's an improbable drive not an improbability drive. Also it's in all probability a hoax of some sort, but it'd be cool if it wasn't.

30
General Disconation / What is congress suing Obama over.
« on: July 30, 2014, 09:05:46 PM »
What is congress suing Obama over.

The articles just say like "overstepping bounds" but like don't cite any specific executive act so

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